m88 review
Selected font size:T|T
m88 live casino games
Plagiarism (Pestis) is a natural epidemic infectious disease caused by plague bacteria。Between wild rodents。The main manifestation of clinical manifestations as high fever、Symptoms of severe toxia、lymphatic swelling and pain、bleeding tendency、Special inflammation of the lungs。
This disease is recorded before 2000。Three major popularity in the world，The first occurred in the 6th century AD，Pass from the Mediterranean region to Europe，Death nearly 100 million people; the second occurred in the 14th century，Paves Europe、Ya、Africa; the third time is 18th century，Propagate 32 countries。In the 14th century, it spread to my country。1793 "" Dead Rat "by Yunnan Daonan described at that time" the rat death for less than a few days，People die as if they are blocked "。Fully explained that it was very rampant in my country at that time。After liberation，my country ’s world plague has basically been eliminated，But the natural epidemic place still exists。
As far as the world is concerned，The peak of onset occurred in the 1970s，2756 cases in the world in 1974，Since the 1990s，The average distribution of patients in Asia、Africa and America，In 1994，Taking the outbreak of Sulatbon, India，693 cases in total。More than 2000 cases reported in the world in recent years。my country 1994 is 7 cases，12 cases in 1995，98 cases in 1996。
I. The biological characteristics of the plague
Gorilla bacteria are short Gram -positive bacteria，New separation strains are dyed with Meilan or Jimsa，Show heavy dyeing at both ends，Polaries (or sealing sets)。During the lesion specimen in and during the first generation m88 best betting websiteof cultivation，Estaline garden shape。growth in the liquid medium is in short chain arrangement。
Ben bacteria are oxygen and concentrated anaerobic bacteria，The optimal temperature is 27-28 ℃，An animal blood is added to the medium for the first time，sodium sulfate, etc. to promote growth，On platelets，28 ℃ Cultivated for 48 hours，growth to opaque，Central Breakage，Ensable hemo，The edge is lace -like colonies，This colonies are characteristic of the bacteria。Incubation 24 hours in the liquid medium gradually forms flocculent precipitation，48 hours form a thin bacteria film on the surface of the liquid，Vertical wires grow from the fungus film to the bottom of the pipe，Belong stalactites。Plagobacterium has strong resistance to the outside world，in cold、Under the condition of humidity，Not easy to die，can still survive at -30 ° C，It can still survive under the conditions of 5-10 ℃。Key direct sunlight 1 to 4 hours，A few weeks to survive in dry sputum and flea dung，Can survive in frozen corpses for 4 to 5 months，But for general disinfection agents、The resistance of the bactericide is not strong。Chainithin、Kanamycin and tetracycline sensitivity。
2. The pathogenicity and immunization of Ourgobacteria
The pathogenic disease is a multi -passing infection，Local pod film，A variety of toxic antigens，Toxins and toxic enzymes，hyaluronase，Cadefibinase and other diseases。Plagiarbolia strains have the following antigen components and toxins。
(1) Fi (Fraction I) antigen in the pod has two antigen components in the pod，One is polysaccharide protein (f ~ i)，Another kind of protein。Only when it is cultivated at 37 ° C，It has the effect of resisting the degradation。
(2) Verimal V/W (VirulcNCE) antigen on the surface of the bacteria，V antigen is protein，It has a protective effect; W antigen is lipoprotein，Can't make guinea pigs protection，V/W antigen binding can promote the production of a film，Inhibiting phagocytosis，and have the ability to protect bacteria growth and reproduction in the cell，So，Related to the invasion force。
(3) Murine Toxin (Murine Toxin) The external toxin (toxic protein) produced by the plague，The main role is to inhibit the restoration of coenzymes，Damage to the internal mitochondrial respiratory of myocardial cells，Poisonous Mochidal slightly vascular system and lymphatic endothelial cells，Causes blood pressure and shock，can make the liver、Degeneration of M88 Online Live Casinokidney and myocardial tissue、bleeding、Necrosis。Strong antigenicity of mouse toxins，Can be made into toxins。
(4) The nature of vanoxin in general Gram -negatives is the same.，But toxicity is strong，heat resistance，Can cause fever、Persistent intravascular coagulation，and toxic shock。
(5) Pesticin (Pesticin I) has the effect of killing other bacteria，The invasion force is related，helps to attack and spread。
immune human body has no natural immunity to plague，The crowd is generally susceptible to plague，Gender -free age differences。Those who have suffered from plague can get persistent immunity，Few infection。
3, popular features
1. Plague natural epidemics have many natural epidemic places around the world，Wild Rat plague continues to exist for a long time。Plague on earth is mostly passed from wild rats to house rat，caused by the mouse caused by the mouse。Occasionally due to hunting (capture marmot)、Examination、Construction、Military activities enter the epidemic area and are infected。
2. Popular diseases are mostly spread out of the epidemic district transportation，Form an exogenous plague，Causes popularity、Big Popular。
3. Seasonality is related to mouse activity and mouse flea breeding.。The plague on earth is mostly from June to September。Polygonic plague is mostly popular after October。
4. hidden infection in the epidemic area has been found to be symptomatic.。
Four, the source of infection
Plague is a typical natural epidemic disease，Before popular on earth，Generally popular among rats。The source of the plague infection between the mouse (store owner) has a wild mouse、Mouse、Fox、Wolf、Cat、Leopard, etc.，Among them, the owner and marmot are the most important。Yellow breasts in the mouse、Brown Rat and Black House are an important source of infection on earth。Patients in each type can become the source of infection，The most important thing in a lung -type plague。Early blood in the bloody plague is contagious。Gonads only played a source of infection after the abscess was ulcerated or was blood -sucking by fleas。
The spread of animal and human plague is mainly based on mouse fleas。After the mouse flea is absorbed by the mice containing the diseased bacteria，Bacteria breed in large quantities in fleas，Formation of bacterial embolism to block the stomach，When the fleas are inhaled and blood，Bacterial blood reflux，Inject animals or human body。Flea dung also contains plagorus，M88 Online Live CasinoIt can enter the skin because itching。This way of spreading this kind of "rat → flea → man" is the main way of spreading the plague。 In addition，Earth plague can also directly contact the skin of the animal after the beasts infected by the slaughter、Blood、meat or patient's sputum、Pus is infected with damaged skin or mucosa，Invasion of damage wound，Or inhalation of gas -soluble infection with the bacteria。
5. Common types of plague
The incubation period is generally 2 to 5 days。Gland plague or defeated blood -type plague for 2 to 7 days; primary lung plague 1 to 3 days，Even for a few hours;，can be as long as 12 days。
Clinical glands、Lungfang、Blood type and light type four types such as，Except for light type，The symptoms of systemic poisoning in the early stages of each type are roughly the same。
(1) Gland plague accounts for 85-90%。It is mainly transmitted to the mouse of the mouse，When the mouse is bitten by mosquito，Injecting plague into the human skin。Except for the symptoms of whole body poisoning，Features characterized by acute lymphitis。More opportunities to bite by fleas due to lower limbs，Therefore inguinal lymphitis is most common，about 70%; followed by armpits，Neck and mandibular。You can also be involved in several parts of lymph nodes at the same time。Local lymph nodes are sick and swelling and pain，Symptoms of the 2 to 3 days after the disease quickly intensify，Red、swelling、Hot、Pain and sticking to the surrounding tissue into pieces，Strong tenderness，Patients are at the persistent position。lymph nodes after 4 ～ 5 days lymph nodes，Alice the condition。Partial development can be developed into defeated hemiamal、Severe toxia, heart failure or lung implants die; after treatment with antibiotics，Disease mortality can be reduced to 5-10%。
(2) Plague or secondary pulmonary plague is directly caused by the inhaled air.，Very contagious，It is easy to expand popularity in the cold season，The most dangerous of this type of disease。Secondary pulmonary plague in patients with gonad plague or sepiocylocores invaded complicated pneumonia in their own lungs，Breathing by patients，Disease mortality is extremely high。Successful onset of this type，Quick development，Except for severe poisoning symptoms，Starty chest pain occurs within 24 to 36 hours of the onset、Cough、Priced a lot of bubble blood or bright red sputum; breathing rapid，and quickly present breathing difficulties and purple gangs; lungs M88 Online Live Casinocan be heard and a small amount of scattered wet Luo Yin、pleural friction can appear; chest X -ray showing bronchitis expression，Extremely inconsistent with the severity of the condition。If the rescue is not timely，Within 2-3 days，Due to heart failure，Breeding and death。
(3) The blood -type plague is also called a hairpin。can be primary or secondary。Primary -style plague due to poor immune function，More bacteria，Strong toxic power，So the speed of development。Frequent suddenly high fever or body temperature is not rising，Unclear consciousness，Delicate or coma。lymphatic swelling。Skin mucosal bleeding、Nose、Vomiting、Blood or hematuria、DIC and heart failure，Mostly died within 24 hours after the onset，rarely exceed 3 days。Disease mortality is as high as 100%。Due to extensive skin bleeding、Essence、Zi Yan、Necrosis，Therefore, the corpse is purple and black after death，Commonly known as "Black Death"。
Second -segmented plague，Can be plague、Gland plague development，The symptoms are different。
(4) Light -type plague is also known as hob，Heat light，Patients can work as usual，Local lymph nodes，Mild tenderness，Occasionally pus。Blood culture positive。It is more common in the beginning of popularity、Last phase or prevention person。
6. Other rare types
1. Skin plague germs invade the local skin, painful erythema，Developed into blisters after a few hours，Forming pustules，Black scoop skin on the surface，There are dark red infiltrations around，Base is hard ulcers，Like skin anthrax。Occasionally a whole body pustular，Similar to smallpox，The name of the sky -like plague。
2． Metronous encephalitis type is mostly secondary to glandular or other mouse epidemics。Symptoms of cerebral membrane cerebral inflammation、Signs、cerebrospinal fluid is purulent，Coating or culture can detect Optobacterium。
3． Eye germs invade the conjunctiva，Validity conjunctivitis。
4． Except for the symptoms of enteritis, except for the symptoms of the whole body，There are diarrhea and mucus blood samples，and vomiting、Abdominal pain、In the hurry，Gelag can be detected。
5． The throat type is hidden infection。Symptoms without symptoms，But Gorilla can be separated from the nasopharynx。Seeing the preventioner。
7. Clinical testing and sample acquisition
Pay attention to strengthening clinical testing of suspicious animals in the epidemic area or natural epidemic m88 reviewarea with an epidemic area or natural epidemic in rats，Samples (blood、Some secretions or respiratory secretions in the game)，For the suspected plague corpse，Disease solution or puncture is sent to the relevant laboratory for bacterial examination。serum science should use double serum to rise by more than 4 times as the basis for testing and diagnosis。(picking from Survival Wild Animal Epidemic Disease Monitoring Network)
Supply: Qi Jun Editor: Zhang Yuanlin
